Corin Antikörper (C-Term)

Produktnummer ABIN2782724

Der Kaninchen Polyklonal anti-Corin Antikörper wird verwendet zum Nachweis von Corin in Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio) und Hund. Er wurde validiert für WB.

Kurzübersicht für Corin Antikörper (C-Term) (ABIN2782724)

Target: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Corin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Corin Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: Corin Antibody - C-terminal region

Sequenz: MGNKMPFKLQ EGEVRIIPLE QCQSYFDMKT ITNRMICAGY ESGTVDSCMG

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 93%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Corin. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Mouse Corin

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46746-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Corin

Target: Corin (CORIN) (Corin, Serine Peptidase (CORIN))

Andere Bezeichnung: Corin

Hintergrund:

Background Information: Corin is a Serine-type endopeptidase involved in atrial natriuretic peptide hormone (NPPA) processing. It converts through proteolytic cleavage the non-functional propeptide NPPA into the active hormone, thereby regulating blood pressure in heart and promoting natriuresis, diuresis and vasodilation. Proteolytic cleavage of pro-NPPA also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Corin also acts as a regulator of sodium reabsorption in kidney. May also process pro-NPPB the B-type natriuretic peptide.

Alternative Symbols: L, Lrp4, AV273130

Protein Name: Atrial natriuretic peptide-converting enzyme

Molekulargewicht: 123kDa

Gen-ID: 53419

NCBI Accession: NP_058565

UniProt: Q9Z319

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones