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EBP Antikörper (N-Term)

EBP Reaktivität: Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2782722
  • Target Alle EBP Antikörper anzeigen
    EBP (Emopamil Binding Protein (Sterol Isomerase) (EBP))
    Bindungsspezifität
    • 14
    • 8
    • 7
    • 7
    • 4
    • 4
    • 1
    • 1
    N-Term
    Reaktivität
    Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen
    Wirt
    • 41
    Kaninchen
    Klonalität
    • 41
    Polyklonal
    Konjugat
    • 15
    • 6
    • 6
    • 6
    • 4
    • 4
    Dieser EBP Antikörper ist unkonjugiert
    Applikation
    • 33
    • 33
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    LVIEGWFVLY YEDLLGDQAF LSQLWKEYAK GDSRYILGDN FTVCMETITA
    Homologie
    Cow: 93%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 85%, Pig: 93%, Rabbit: 93%, Rat: 85%
    Produktmerkmale
    This is a rabbit polyclonal antibody against EBP. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human EBP
    Top Product
    Discover our top product EBP Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 230 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    EBP (Emopamil Binding Protein (Sterol Isomerase) (EBP))
    Andere Bezeichnung
    EBP (EBP Produkte)
    Synonyme
    cdpx2 antikoerper, cho2 antikoerper, cpx antikoerper, cpxd antikoerper, zgc:91895 antikoerper, CDPX2 antikoerper, CHO2 antikoerper, CPX antikoerper, CPXD antikoerper, AI255399 antikoerper, Pabp antikoerper, Td antikoerper, mSI antikoerper, emopamil binding protein (sterol isomerase) antikoerper, emopamil binding protein (sterol isomerase) L homeolog antikoerper, phenylalkylamine Ca2+ antagonist (emopamil) binding protein antikoerper, Ebp antikoerper, ebp.L antikoerper, ebp antikoerper, EBP antikoerper
    Hintergrund
    EBP is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in EBP gene cause Chondrodysplasia punctata 2 (CDPX2, also known as Conradi-Hunermann syndrome).Emopamil-binding protein (EBP) is an integral membrane protein of the endoplasmic reticulum. It is a high affinity binding protein for the antiischemic phenylalkylamine Ca2+ antagonist [3H]emopamil and the photoaffinity label [3H]azidopamil. It is similar to sigma receptors and may be a member of a superfamily of high affinity drug-binding proteins in the endoplasmic reticulum of different tissues. EBP shares structural features with bacterial and eukaryontic drug transporting proteins. It has four putative transmembrane segments and contains two conserved glutamate residues which may be involved in the transport of cationic amphiphilics. Another prominent feature of EBP is its high content of aromatic amino acid residues (>23 % ) in its transmembrane segments. These aromatic amino acid residues have been suggested to be involved in the drug transport by the P-glycoprotein. Mutations in this gene cause Chondrodysplasia punctata 2 (CDPX2, also known as Conradi-Hunermann syndrome).
    Alias Symbols: CDPX2, CHO2, CPX, CPXD
    Protein Interaction Partner: UBC, MITF, VKORC1, APP, ELAVL1, ESRRG, EBPL,
    Protein Size: 230
    Molekulargewicht
    26 kDa
    Gen-ID
    10682
    NCBI Accession
    NM_006579, NP_006570
    UniProt
    Q15125
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