ZMPSTE24 Antikörper (N-Term)

Produktnummer ABIN2782696

Produktdetails anti-ZMPSTE24 Antikörper

Target: ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZMPSTE24 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LYSETEGTLI LLFGGIPYLW RLSGRFCGYA GFGPEYEITQ SLVFLLLATL

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 79%, Rabbit: 100%, Rat: 91%, Zebrafish: 90%

Produktmerkmale: This is a rabbit polyclonal antibody against ZMPSTE24. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ZMPSTE24

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 475 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ZMPSTE24

Target: ZMPSTE24 (Zmpste24) (Zinc Metalloproteinase, Ste24 (Zmpste24))

Andere Bezeichnung: ZMPSTE24 (Zmpste24 Produkte)

Synonyme: DDBDRAFT_0189115 antikoerper, DDBDRAFT_0237846 antikoerper, DDB_0189115 antikoerper, DDB_0237846 antikoerper, F2N1.21 antikoerper, F2N1_21 antikoerper, STE24 antikoerper, FACE-1 antikoerper, FACE1 antikoerper, HGPS antikoerper, PRO1 antikoerper, Ste24p antikoerper, A530043O15Rik antikoerper, D030046F19 antikoerper, Face-1 antikoerper, MADB antikoerper, fi45a02 antikoerper, wu:fi45a02 antikoerper, zgc:55655 antikoerper, zinc metallopeptidase STE24 antikoerper, zinc metallopeptidase STE24 L homeolog antikoerper, CAAX prenyl protease antikoerper, Peptidase family M48 family protein antikoerper, zinc metallopeptidase, STE24 antikoerper, zinc metallopeptidase, STE24 homolog antikoerper, ZMPSTE24 antikoerper, zmpste24.L antikoerper, zmpste24 antikoerper, ATSTE24 antikoerper, Zmpste24 antikoerper

Hintergrund: ZMPSTE24 is a member of the peptidase M48A family. This protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in ZMPSTE24 gene have been associated with mandibuloacral dysplasia and restrictive dermopathy.The protein encoded by this gene is a zinc metalloprotease similar to yeast Ste24p. It is an integral membrane protein belonging to peptidase family M48 and is found in the endoplasmic reticulum and possibly in the Golgi compartment. It is thought to be involved in the proteolytic processing of farnesylated proteins.
Alias Symbols: FACE-1, FACE1, FLJ14968, STE24, Ste24p, HGPS, PRO1
Protein Interaction Partner: UBC, BAG3, KIAA2013, TMEM43, MRPL40, MRPS5, SYNJ2BP, ATP6V1H, HNRNPUL1, RAB10, VDAC1, UQCRFS1P1, S100A10, RAB5C, PTPN1, NDUFB7, MGST3, HNRNPF, GALNT2, DDOST, CD55, ELAVL1, MME,
Protein Size: 475

Molekulargewicht: 55 kDa

Gen-ID: 10269

NCBI Accession: NM_005857, NP_005848

UniProt: O75844