DLL1 Antikörper (N-Term)

Produktnummer ABIN2782684

Dieses Anti-DLL1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DLL1 in WB und IHC. Geeignet für Human, Maus, Ratte, Rind (Kuh), Schwein und Kaninchen. Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für DLL1 Antikörper (N-Term) (ABIN2782684)

Target: DLL1 (delta-Like 1 (DLL1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DLL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-DLL1 Antikörper

Bindungsspezifität: N-Term

Sequenz: GSRCALALAV LSALLCQVWS SGVFELKLQE FVNKKGLLGN RNCCRGGAGP

Homologie: Cow: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against DLL1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DLL1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 723 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-DLL1 Antikörper (ABIN2782684)

Caliceti, Aquila, Pannella, Morelli, Fortini, Pinton, Bonora, Hrelia, Pannuti, Miele, Rizzo, Ferrari: "17?-estradiol enhances signalling mediated by VEGF-A-delta-like ligand 4-notch1 axis in human endothelial cells." in: PLoS ONE, Vol. 8, Issue 8, pp. e71440, (2013) (PubMed).

Suprynowicz, Upadhyay, Krawczyk, Kramer, Hebert, Liu, Yuan, Cheluvaraju, Clapp, Boucher, Kamonjoh, Randell, Schlegel: "Conditionally reprogrammed cells represent a stem-like state of adult epithelial cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 49, pp. 20035-40, (2012) (PubMed).

Details zu DLL1

Target: DLL1 (delta-Like 1 (DLL1))

Andere Bezeichnung: DLL1

Hintergrund: DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication.DLL1 is a human homolog of the Notch Delta ligand and is a member of the delta/serrate/jagged family. It plays a role in mediating cell fate decisions during hematopoiesis. It may play a role in cell-to-cell communication. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: DELTA1, Delta, DL1
Protein Interaction Partner: EPN1, UBC, MIB1, MAGI2, CNKSR3, POFUT1, DLL1, MFNG, ADAM10, NOTCH3, NOTCH2, NOTCH1, NOV, PSEN1, MAGI1,
Protein Size: 723

Molekulargewicht: 78 kDa

Gen-ID: 28514

NCBI Accession: NM_005618, NP_005609

UniProt: O00548

Pathways: Notch Signalweg, Stem Cell Maintenance