DDOST Antikörper (N-Term)

Produktnummer ABIN2782672

Der Kaninchen Polyklonal anti-DDOST Antikörper wird verwendet zum Nachweis von DDOST in Proben von Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Schaf. Er wurde validiert für WB.

Kurzübersicht für DDOST Antikörper (N-Term) (ABIN2782672)

Target: DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))

Reaktivität: Human, Maus, Ratte, Hund, Zebrafisch (Danio rerio), Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DDOST Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DDOST Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: DDOST Antibody - N-terminal region

Sequenz: SPSVEDFGGN INVETISAFI DGGGSVLVAA SSDIGDPLRE LGSECGIEFD

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against DDOST. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DDOST

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8099148

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu DDOST

Target: DDOST (Dolichyl-diphosphooligosaccharide--Protein Glycosyltransferase (DDOST))

Andere Bezeichnung: DDOST

Hintergrund:

Background Information: DDOST is a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. DDOST is also implicated in the processing of advanced glycation endproducts (AGEs), which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.

Gene Name: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase

Alternative Symbols: OST, WBP1, AGER1, CDG1R, GATD6, OST48, OKSWcl45

Protein Name: Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

Molekulargewicht: 46kDa

Gen-ID: 1650

NCBI Accession: NP_005207

UniProt: Q5VWA5

Pathways: Cell RedoxHomeostasis