CPT1B Antikörper (Middle Region)

Produktnummer ABIN2782633

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CPT1B in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Schaf und Zebrafisch (Danio rerio) und wurde in 4+ Publikationen erwähnt.

Kurzübersicht für CPT1B Antikörper (Middle Region) (ABIN2782633)

Target: CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh), Schaf, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CPT1B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CPT1B Antikörper

Bindungsspezifität: Middle Region

Sequenz: DLEMQFQRIL DDPSPPQPGE EKLAALTAGG RVEWAQARQA FFSSGKNKAA

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 86%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against CPT1B. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CPT1B

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 772 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CPT1B Antikörper (ABIN2782633)

Fiserova, Trinh, Elkalaf, Vacek, Heide, Martinkova, Bechynska, Kosek, Hajslova, Fiser, Tousek, Polak: "Isoprenaline modified the lipidomic profile and reduced β-oxidation in HL-1 cardiomyocytes: In vitro model of takotsubo syndrome." in: Frontiers in cardiovascular medicine, Vol. 9, pp. 917989, (2022) (PubMed).

Jiang, Ma, Li, Cao, Wang, Zhang, Liu: "Effects of neonatal dexamethasone administration on cardiac recovery ability under ischemia-reperfusion in 24-wk-old rats." in: Pediatric research, Vol. 80, Issue 1, pp. 128-35, (2016) (PubMed).

Li, Liu, Ma, Guan, Cao, Tian, Zhang: "Enhancement of Glucose Metabolism via PGC-1α Participates in the Cardioprotection of Chronic Intermittent Hypobaric Hypoxia." in: Frontiers in physiology, Vol. 7, pp. 219, (2016) (PubMed).

Wolf-Johnston, Hanna-Mitchell, Buffington, Shinde, Roppolo, Mayer, Birder: "Alterations in the non-neuronal acetylcholine synthesis and release machinery in esophageal epithelium." in: Life sciences, Vol. 91, Issue 21-22, pp. 1065-9, (2012) (PubMed).

Details zu CPT1B

Target: CPT1B (Carnitine Palmitoyltransferase 1B (Muscle) (CPT1B))

Andere Bezeichnung: CPT1B

Hintergrund: The protein encoded by this gene, a member of the carnitine/choline acetyltransferase family, is the rate-controlling enzyme of the long-chain fatty acid beta-oxidation pathway in muscle mitochondria. This enzyme is required for the net transport of long-
Alias Symbols: CPT1-M, KIAA1670, M-CPT1, CPTI, CPT1M, MCPT1, CPTI-M, MCCPT1
Protein Interaction Partner: C2orf57,
Protein Size: 772

Molekulargewicht: 88 kDa

Gen-ID: 1375

NCBI Accession: NM_004377, NP_004368

UniProt: Q92523

Pathways: AMPK Signaling, Monocarboxylic Acid Catabolic Process