TMPRSS11D Antikörper (N-Term)

Produktnummer ABIN2782621

Produktdetails anti-TMPRSS11D Antikörper

Target: TMPRSS11D (Transmembrane Protease, serine 11D (TMPRSS11D))

Bindungsspezifität: N-Term

Reaktivität: Human, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMPRSS11D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: RSSFQLLNVE YNSQLNSPAT QEYRTLSGRI ESLITKTFKE SNLRNQFIRA

Homologie: Guinea Pig: 79%, Horse: 79%, Human: 100%, Rabbit: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TMPRSS11D. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TMPRSS11D

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 418 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TMPRSS11D Antikörper (ABIN2782621)

Matsushima, Takahashi, Nakaya, Maezawa, Miki, Nakamura, Ohgushi, Yasuoka: "Human airway trypsin-like protease stimulates human bronchial fibroblast proliferation in a protease-activated receptor-2-dependent pathway." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 290, Issue 2, pp. L385-95, (2006) (PubMed).

Details zu TMPRSS11D

Target: TMPRSS11D (Transmembrane Protease, serine 11D (TMPRSS11D))

Andere Bezeichnung: TMPRSS11D (TMPRSS11D Produkte)

Synonyme: HAT antikoerper, AST antikoerper, AsP antikoerper, BC020151 antikoerper, Asp antikoerper, Tmprss11d antikoerper, transmembrane protease, serine 11D antikoerper, transmembrane protease, serine 11d antikoerper, transmembrane protease serine 11D antikoerper, TMPRSS11D antikoerper, Tmprss11d antikoerper, LOC100720850 antikoerper

Hintergrund: TMPRSS11D is a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38 % identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38 % identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.
Alias Symbols: HAT, MGC150587, MGC150588
Protein Size: 418

Molekulargewicht: 46 kDa

Gen-ID: 9407

NCBI Accession: NM_004262, NP_004253

UniProt: O60235

Pathways: Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process