TMPRSS11D Antikörper (N-Term)

Produktnummer ABIN2782621

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-TMPRSS11D Antikörper (ABIN2782621) detektiert spezifisch TMPRSS11D in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für TMPRSS11D Antikörper (N-Term) (ABIN2782621)

Target: TMPRSS11D (Transmembrane Protease, serine 11D (TMPRSS11D))

Reaktivität: Human, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TMPRSS11D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-TMPRSS11D Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: TMPRSS11D Antibody - N-terminal region

Sequenz: RSSFQLLNVE YNSQLNSPAT QEYRTLSGRI ESLITKTFKE SNLRNQFIRA

Homologie: Guinea Pig: 79%, Horse: 79%, Human: 100%, Rabbit: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against TMPRSS11D. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human TMPRSS11D

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8114409

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TMPRSS11D Antikörper (ABIN2782621)

Matsushima, Takahashi, Nakaya, Maezawa, Miki, Nakamura, Ohgushi, Yasuoka: "Human airway trypsin-like protease stimulates human bronchial fibroblast proliferation in a protease-activated receptor-2-dependent pathway." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 290, Issue 2, pp. L385-95, (2006) (PubMed).

Details zu TMPRSS11D

Target: TMPRSS11D (Transmembrane Protease, serine 11D (TMPRSS11D))

Andere Bezeichnung: TMPRSS11D

Hintergrund:

Background Information: TMPRSS11D is a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38 % identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.This gene encodes a trypsin-like serine protease released from the submucosal serous glands onto mucous membrane. It is a type II integral membrane protein and has 29-38 % identity in the sequence of the catalytic region with human hepsin, enteropeptidase, acrosin, and mast cell tryptase. The noncatalytic region has little similarity to other known proteins. This protein may play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions.

Gene Name: Transmembrane protease, serine 11D

Alternative Symbols: ASP, HAT

Protein Name: Transmembrane protease serine 11D

Molekulargewicht: 46kDa

Gen-ID: 9407

NCBI Accession: NP_004253

UniProt: O60235

Pathways: Positive Regulation of Peptide Hormone Secretion, Regulation of Carbohydrate Metabolic Process