FcRn Antikörper (N-Term)

Produktnummer ABIN2782616

Der Kaninchen Polyklonal anti-FcRn Antikörper wird verwendet zum Nachweis von FcRn in Proben von Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd und Schaf. Er wurde validiert für WB und IHC.

Kurzübersicht für FcRn Antikörper (N-Term) (ABIN2782616)

Target: FcRn (neonatal Fc Receptor (FcRn))

Reaktivität: Human, Maus, Rind (Kuh), Hund, Meerschweinchen, Pferd, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FcRn Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-FcRn Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: FCGRT Antibody - N-terminal region

Sequenz: GWLGPQQYLS YNSLRGEAEP CGAWVWENQV SWYWEKETTD LRIKEKLFLE

Homologie: Cow: 79%, Dog: 79%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 79%, Sheep: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against FCGRT. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human FCGRT

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8106270

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu FcRn

Target: FcRn (neonatal Fc Receptor (FcRn))

Andere Bezeichnung: FCGRT

Hintergrund:

Targeted Subunit: p51

Background Information: FCGRT binds to the Fc region of monomeric immunoglobulins gamma. It mediates the uptake of IgG from milk. It plays a possible role in transfer of immunoglobulin G from mother to fetus.

Gene Name: Fc fragment of IgG, receptor, transporter, alpha

Alternative Symbols: FCRN, alpha-chain

Protein Name: IgG receptor FcRn large subunit p51

Molekulargewicht: 40kDa

Gen-ID: 2217

NCBI Accession: NP_004098

UniProt: P55899

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process