HRK Antikörper (N-Term)

Produktnummer ABIN2782598

Der Kaninchen Polyklonal Anti-HRK-Antikörper wurde für WB validiert. Er ist geeignet, HRK in Proben von Human, Maus, Ratte, Rind (Kuh), Hund und Kaninchen zu detektieren. Es ist 1 Publikation verfügbar.

Kurzübersicht für HRK Antikörper (N-Term) (ABIN2782598)

Target: HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HRK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HRK Antikörper

Bindungsspezifität: N-Term

Sequenz: MCPCPLHRGR GPPAVCACSA GRLGLRSSAA QLTAARLKAL GDELHQRTMW

Homologie: Cow: 100%, Dog: 100%, Human: 100%, Mouse: 83%, Rabbit: 100%, Rat: 83%

Produktmerkmale: This is a rabbit polyclonal antibody against HRK. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HRK

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 91 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HRK Antikörper (ABIN2782598)

Lucas, Milani, Butterworth, Carmell, Scott, Clark, Cohen, Varadarajan: "High CIP2A levels correlate with an antiapoptotic phenotype that can be overcome by targeting BCL-XL in chronic myeloid leukemia." in: Leukemia, Vol. 30, Issue 6, pp. 1273-81, (2016) (PubMed).

Details zu HRK

Target: HRK (Harakiri, BCL2 Interacting Protein (Contains Only BH3 Domain) (HRK))

Andere Bezeichnung: HRK

Hintergrund: Activator of apoptosis Hrk regulates apoptosis through interaction with death-repressor proteins Bcl-2 and Bcl-X(L). The HRK protein lacks significant homology to other BCL2 family members except for an 8-amino acid region that was similar to the BCL2 hom
Alias Symbols: DP5, HARAKIRI
Protein Interaction Partner: BCL2L1, ELAVL1, BAD, BCL2L2, C1QBP, BCL2A1, BCL2, MCL1, BNC1,
Protein Size: 91

Molekulargewicht: 10 kDa

Gen-ID: 8739

NCBI Accession: NM_003806, NP_003797

UniProt: O00198