NMT1 Antikörper (N-Term)

Produktnummer ABIN2782574

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-NMT1 Antikörper (ABIN2782574) detektiert spezifisch NMT1 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Schwein, Kaninchen, Zebrafisch (Danio rerio), Hund und Pferd.

Kurzübersicht für NMT1 Antikörper (N-Term) (ABIN2782574)

Target: NMT1 (N-Myristoyltransferase 1 (NMT1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Schwein, Kaninchen, Zebrafisch (Danio rerio), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NMT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NMT1 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: NMT1 Antibody - N-terminal region

Sequenz: TMEEASKRSY QFWDTQPVPK LGEVVNTHGP VEPDKDNIRQ EPYTLPQGFT

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against NMT1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NMT1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46299-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-NMT1 Antikörper (ABIN2782574)

Takamune, Gota, Misumi, Tanaka, Okinaka, Shoji: "HIV-1 production is specifically associated with human NMT1 long form in human NMT isozymes." in: Microbes and infection / Institut Pasteur, Vol. 10, Issue 2, pp. 143-50, (2008) (PubMed).

Details zu NMT1

Target: NMT1 (N-Myristoyltransferase 1 (NMT1))

Andere Bezeichnung: NMT1

Hintergrund:

Background Information: Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1).

Gene Name: N-myristoyltransferase 1

Alternative Symbols: NMT

Protein Name: Glycylpeptide N-tetradecanoyltransferase 1

Molekulargewicht: 57kDa

Gen-ID: 4836

NCBI Accession: NP_066565

UniProt: P30419

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling