NMT1 Antikörper (N-Term)

Produktnummer ABIN2782574

Dieses Anti-NMT1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von NMT1 in WB. Geeignet für Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Schwein, Kaninchen, Zebrafisch (Danio rerio), Hund und Pferd. Dieses Primary Antibody wurde in 1 Publikation zitiert.

Kurzübersicht für NMT1 Antikörper (N-Term) (ABIN2782574)

Target: NMT1 (N-Myristoyltransferase 1 (NMT1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Schwein, Kaninchen, Zebrafisch (Danio rerio), Hund, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NMT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NMT1 Antikörper

Bindungsspezifität: N-Term

Sequenz: TMEEASKRSY QFWDTQPVPK LGEVVNTHGP VEPDKDNIRQ EPYTLPQGFT

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against NMT1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NMT1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 496 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-NMT1 Antikörper (ABIN2782574)

Takamune, Gota, Misumi, Tanaka, Okinaka, Shoji: "HIV-1 production is specifically associated with human NMT1 long form in human NMT isozymes." in: Microbes and infection / Institut Pasteur, Vol. 10, Issue 2, pp. 143-50, (2008) (PubMed).

Details zu NMT1

Target: NMT1 (N-Myristoyltransferase 1 (NMT1))

Andere Bezeichnung: NMT1

Hintergrund: Myristate, a rare 14-carbon saturated fatty acid, is cotranslationally attached by an amide linkage to the N-terminal glycine residue of cellular and viral proteins with diverse functions. N-myristoyltransferase catalyzes the transfer of myristate from CoA to proteins. N-myristoylation appears to be irreversible and is required for full expression of the biologic activities of several N-myristoylated proteins, including the alpha subunit of the signal-transducing guanine nucleotide-binding protein (G protein) GO (GNAO1).
Alias Symbols: NMT
Protein Interaction Partner: C14orf166, RTCB, DIMT1, NELFB, EDC4, IGF2BP3, PDCD6, POLR1C, EIF2B2, EIF2B3, YBX3, RPL38, RPL23A, RPL19, RFC4, QARS, PA2G4, YBX1, HNRNPM, MRE11A, MAP2, ILF2, IARS, HNRNPU, FLII, FKBP3, DYNC1LI2, DHX9, DDX1, ABCF1, nef, UBC, CSNK2A1, gag, ARL5A, CABP2, MAR
Protein Size: 496

Molekulargewicht: 57 kDa

Gen-ID: 4836

NCBI Accession: NM_021079, NP_066565

UniProt: P30419

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling