NUP62 Antikörper (N-Term)

Produktnummer ABIN2782528

Der Kaninchen Polyklonal Anti-NUP62 Antikörper wurde für WB und IF validiert. Er ist geeignet, NUP62 in Proben von Human, Maus, Ratte, Hund und Meerschweinchen zu detektieren.

Kurzübersicht für NUP62 Antikörper (N-Term) (ABIN2782528)

Target: NUP62 (Nucleoporin 62kDa (NUP62))

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NUP62 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Produktdetails anti-NUP62 Antikörper

Bindungsspezifität: N-Term

Sequenz: SGFNFGGTGA PTGGFTFGTA KTATTTPATG FSFSTSGTGG FNFGAPFQPA

Homologie: Dog: 100%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against NUP62. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NUP62

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 522 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NUP62

Target: NUP62 (Nucleoporin 62kDa (NUP62))

Andere Bezeichnung: NUP62

Hintergrund: The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. NUP62 is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals.The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins are the main components of the nuclear pore complex in eukaryotic cells. The protein encoded by this gene is a member of the FG-repeat containing nucleoporins and is localized to the nuclear pore central plug. This protein associates with the importin alpha/beta complex which is involved in the import of proteins containing nuclear localization signals. Multiple transcript variants of this gene encode a single protein isoform.
Alias Symbols: DKFZp547L134, FLJ20822, FLJ43869, IBSN, MGC841, SNDI, p62
Protein Interaction Partner: CEP57L1, CCDC150, SSC5D, KANSL1, CCDC153, TXLNA, AGR3, C1orf216, IKBIP, HAUS1, KLHL32, IFT20, MYO15B, CENPU, CCDC121, CCDC146, THAP1, CRCT1, CCHCR1, KRT20, NUP54, PHF21A, CCDC53, BLOC1S6, ISCU, XPO6, OIP5, NXF1, SNAPC5, NUTF2, ABI2, NUPL1, ADAM15, UBC, SM
Protein Size: 522

Molekulargewicht: 53 kDa

Gen-ID: 23636

NCBI Accession: NM_012346, NP_036478

UniProt: P37198

Pathways: EGFR Signaling Pathway, SARS-CoV-2 Protein Interaktom