SMC4 Antikörper (N-Term)

Produktnummer ABIN2782504

Der Kaninchen Polyklonal anti-SMC4 Antikörper wird verwendet zum Nachweis von SMC4 in Proben von Human, Maus, Ratte, Meerschweinchen, Hund, Pferd, Rind (Kuh), Kaninchen und Schwein. Er wurde validiert für WB.

Kurzübersicht für SMC4 Antikörper (N-Term) (ABIN2782504)

Target: SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Hund, Pferd, Rind (Kuh), Kaninchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMC4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SMC4 Antikörper

Bindungsspezifität: N-Term

Sequenz: SGRTESPATA AETASEELDN RSLEEILNSI PPPPPPAMTN EAGAPRLMIT

Homologie: Cow: 86%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 100%, Pig: 86%, Rabbit: 93%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SMC4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SMC4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1288 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SMC4

Target: SMC4 (Structural Maintenance of Chromosomes 4 (SMC4))

Andere Bezeichnung: SMC4

Hintergrund: SMC4 is the central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.
Alias Symbols: CAPC, SMC4L1, hCAP-C, CAP-C, SMC-4
Protein Interaction Partner: UBC, SUMO2, LGR4, RPA3, RPA2, RPA1, RNF2, NCAPH, SMC2, SSSCA1, NCAPD2, TBC1D4, PLEC, AP3S1, CDK9, NCAPG, CCAR2, RABL6, TOPBP1, FBXO6, UBD, HDAC11, MYC, Nfe2l2, NEDD8, CDK2, SIRT7, NCAPH2, NCAPD3, RAD21, TRAF3IP1, SUMO1, HDAC1, tat, DNMT3B,
Protein Size: 1288

Molekulargewicht: 147 kDa

Gen-ID: 10051

NCBI Accession: NM_001002800, NP_001002800

UniProt: Q9NTJ3