Non-Syndromic Hearing Impairment Protein 5 (GSDME) (C-Term) Antikörper

Produktnummer ABIN2782489

Der Kaninchen Polyklonal anti-Non-Syndromic Hearing Impairment Protein 5 Antikörper wird verwendet zum Nachweis von Non-Syndromic Hearing Impairment Protein 5 in Proben von Human, Ratte, Hund, Meerschweinchen und Rind (Kuh). Er wurde validiert für WB und IHC.

Kurzübersicht für Non-Syndromic Hearing Impairment Protein 5 (GSDME) (C-Term) Antikörper (ABIN2782489)

Target: Non-Syndromic Hearing Impairment Protein 5 (GSDME)

Reaktivität: Human, Ratte, Hund, Meerschweinchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails

Bindungsspezifität: C-Term

Verwendungszweck: GSDME Antibody - C-terminal region

Sequenz: AALLGTCCKL QIIPTLCHLL RALSDDGVSD LEDPTLTPLK DTERFGIVQR

Homologie: Cow: 85%, Dog: 77%, Guinea Pig: 83%, Human: 100%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against DFNA5. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DFNA5

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46106-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Antigendetails

Target: Non-Syndromic Hearing Impairment Protein 5 (GSDME)

Andere Bezeichnung: GSDME

Hintergrund:

Background Information: Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Three transcript variants encoding two different isoforms have been found for this gene.

Gene Name: gasdermin E

Alternative Symbols: DFNA5, ICERE-1

Protein Name: gasdermin-E

Molekulargewicht: 47kDa

Gen-ID: 1687

UniProt: A4FVA8