HSPA4 Antikörper (N-Term)

Produktnummer ABIN2782467

Produktdetails anti-HSPA4 Antikörper

Target: HSPA4 (Heat Shock 70kDa Protein 4 (HSPA4))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSPA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: PACISFGPKN RSIGAAAKSQ VISNAKNTVQ GFKRFHGRAF SDPFVEAEKS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against HSPA4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HSPA4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 840 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu HSPA4

Target: HSPA4 (Heat Shock 70kDa Protein 4 (HSPA4))

Andere Bezeichnung: HSPA4 (HSPA4 Produkte)

Synonyme: APG-2 antikoerper, HS24/P52 antikoerper, HSPH2 antikoerper, RY antikoerper, hsp70 antikoerper, hsp70RY antikoerper, Hsp110 antikoerper, Hsp70 antikoerper, irp94 antikoerper, 70kDa antikoerper, AI317151 antikoerper, Hsp70RY antikoerper, mKIAA4025 antikoerper, hspa4 antikoerper, wu:fi30e11 antikoerper, zgc:55743 antikoerper, zgc:77413 antikoerper, hs24/p52 antikoerper, hspa4-a antikoerper, osp94 antikoerper, pg-2 antikoerper, hspa4l antikoerper, wu:fc41d05 antikoerper, wu:fi59h02 antikoerper, wu:fj35c08 antikoerper, zgc:55506 antikoerper, heat shock protein family A (Hsp70) member 4 antikoerper, heat shock protein family A member 4 antikoerper, heat shock protein 4 antikoerper, heat shock protein 4b antikoerper, heat shock protein family A (Hsp70) member 4 S homeolog antikoerper, heat shock protein 4a antikoerper, HSPA4 antikoerper, Hspa4 antikoerper, hspa4b antikoerper, hspa4.S antikoerper, hspa4a antikoerper

Hintergrund: HSPA4(Hsp70) belongs to the heat shock protein 70 family. It was isolated as a putative Rictor interacting protein and interaction with membranes acts as a platform for its release into the extracellular environment during its recovery from stress. Hsp70 gene expression in Rheumatoid Arthitis-affected synovial tissue is followed by Hsp70 cell surface expression on fibroblast-like synovial cells growing from RA synovial tissue. Serum Hsp70 levels were increased in Systemic sclerosis patients, and associated with pulmonary fibrosis, skin sclerosis, renal vascular damage, oxidative stress, and inflammation.
Alias Symbols: APG-2, HS24/P52, MGC131852, RY, hsp70, hsp70RY, HSPH2
Protein Interaction Partner: TP53, CDC25C, CDK1, AGTRAP, ERLIN2, HUWE1, Slc12a3, APPBP2, PSMD10, UBC, SUMO2, SUMO3, SIK2, MAP3K11, VHL, UIMC1, PRKCG, PRKCD, STUB1, HIF1A, ENDOG, HSPA8, TRIM5, USP19, PA2G4, WWOX, NDRG1, GZMA, GART, CRMP1, CDKN2A, CARS, PPM1G, PPAT, KARS, FAM114A1, HSP
Protein Size: 840

Molekulargewicht: 94 kDa

Gen-ID: 3308

NCBI Accession: NM_002154, NP_002145

UniProt: P34932