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CRYZ Antikörper (Middle Region)

Der Kaninchen Polyklonal Anti-CRYZ-Antikörper wurde für WB validiert. Er ist geeignet, CRYZ in Proben von Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Schwein und Zebrafisch (Danio rerio) zu detektieren.
Produktnummer ABIN2782462

Kurzübersicht für CRYZ Antikörper (Middle Region) (ABIN2782462)

Target

Alle CRYZ Antikörper anzeigen
CRYZ (Crystallin, zeta (CRYZ))

Reaktivität

Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd, Schwein, Zebrafisch (Danio rerio)

Wirt

  • 10
  • 4
Kaninchen

Klonalität

  • 13
  • 1
Polyklonal

Konjugat

  • 11
  • 1
  • 1
  • 1
Dieser CRYZ Antikörper ist unkonjugiert

Applikation

  • 9
  • 5
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    Middle Region

    Sequenz

    KGIDIIIEML ANVNLSKDLS LLSHGGRVIV VGSRGTIEIN PRDTMAKESS

    Homologie

    Cow: 100%, Dog: 93%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 85%, Rat: 86%, Zebrafish: 93%

    Produktmerkmale

    This is a rabbit polyclonal antibody against CRYZ. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the middle region of human CRYZ
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 329 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    CRYZ (Crystallin, zeta (CRYZ))

    Andere Bezeichnung

    CRYZ

    Hintergrund

    Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. CRYZ is a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low.Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. One pseudogene is known to exist.
    Alias Symbols: DKFZp779E0834, FLJ41475
    Protein Interaction Partner: UBC, TXNRD1, TUBA4A, SPTAN1, PFKP, KRT17, GAPDH, TUBB, IGF2BP3, BASP1, CRYAA,
    Protein Size: 329

    Molekulargewicht

    35 kDa

    Gen-ID

    1429

    NCBI Accession

    NM_001889, NP_001880

    UniProt

    Q08257
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