PAICS Antikörper (N-Term)
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- Target Alle PAICS Antikörper anzeigen
- PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PAICS Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- ATAEVLNIGK KLYEGKTKEV YELLDSPGKV LLQSKDQITA GNAARKNHLE
- Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PAICS. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human PAICS
- Top Product
- Discover our top product PAICS Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 425 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))
- Andere Bezeichnung
- PAICS (PAICS Produkte)
- Synonyme
- cb293 antikoerper, sb:cb293 antikoerper, wu:fa28a05 antikoerper, GB14262 antikoerper, DDBDRAFT_0218550 antikoerper, DDBDRAFT_0230088 antikoerper, DDB_0218550 antikoerper, DDB_0230088 antikoerper, AIRC antikoerper, AS antikoerper, ADE2 antikoerper, ADE2H1 antikoerper, PAIS antikoerper, Ade2h1 antikoerper, Airc antikoerper, ade2 antikoerper, airc antikoerper, paics antikoerper, pais antikoerper, 2610511I09Rik antikoerper, phosphoribosylaminoimidazole carboxylase and phosphoribosylaminoimidazolesuccinocarboxamide synthase antikoerper, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase antikoerper, multifunctional protein ADE2 antikoerper, phosphoribosylaminoimidazole carboxylase antikoerper, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase, gene 2 L homeolog antikoerper, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase antikoerper, PAICS antikoerper, paics antikoerper, LOC551966 antikoerper, Tsp_02239a antikoerper, Tsp_02239 antikoerper, CNE02500 antikoerper, purC/E antikoerper, Paics antikoerper, paics.2.L antikoerper
- Hintergrund
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PAICS is a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ADE2, ADE2H1, AIRC, DKFZp781N1372, MGC1343, MGC5024, PAIS
Protein Interaction Partner: L3MBTL2, PAICS, HUWE1, UBC, FUS, WWOX, QRICH1, SWAP70, FARSB, SUPT5H, SET, PRKCSH, FXR2, NUDT18, SMARCD1, PRKAG1, FN1, NIF3L1, TP53BP1, UNK, GINS4, TMEM177, RPAP1, SSSCA1, TACC3, STUB1, PUM1, ZPR1, UBE2B, TTC1, NDUFV1, GART, UBD, CUL3, CDK2, TERF1, SIRT7,
Protein Size: 425 - Molekulargewicht
- 47 kDa
- Gen-ID
- 10606
- NCBI Accession
- NM_001079524, NP_001072992
- UniProt
- P22234
- Pathways
- Chromatin Binding
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