PAICS Antikörper (N-Term)

Produktnummer ABIN2782454

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PAICS in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd und Kaninchen.

Kurzübersicht für PAICS Antikörper (N-Term) (ABIN2782454)

Target: PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PAICS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PAICS Antikörper

Bindungsspezifität: N-Term

Sequenz: ATAEVLNIGK KLYEGKTKEV YELLDSPGKV LLQSKDQITA GNAARKNHLE

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against PAICS. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PAICS

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 425 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PAICS

Target: PAICS (phosphoribosylaminoimidazole Carboxylase, phosphoribosylaminoimidazole Succinocarboxamide Synthetase (PAICS))

Andere Bezeichnung: PAICS

Hintergrund: PAICS is a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: ADE2, ADE2H1, AIRC, DKFZp781N1372, MGC1343, MGC5024, PAIS
Protein Interaction Partner: L3MBTL2, PAICS, HUWE1, UBC, FUS, WWOX, QRICH1, SWAP70, FARSB, SUPT5H, SET, PRKCSH, FXR2, NUDT18, SMARCD1, PRKAG1, FN1, NIF3L1, TP53BP1, UNK, GINS4, TMEM177, RPAP1, SSSCA1, TACC3, STUB1, PUM1, ZPR1, UBE2B, TTC1, NDUFV1, GART, UBD, CUL3, CDK2, TERF1, SIRT7,
Protein Size: 425

Molekulargewicht: 47 kDa

Gen-ID: 10606

NCBI Accession: NM_001079524, NP_001072992

UniProt: P22234

Pathways: Chromatin Binding