SKAP1 Antikörper (N-Term)

Produktnummer ABIN2782452

Dieses Anti-SKAP1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SKAP1 in WB. Geeignet für Human, Ratte, Maus und Kaninchen.

Kurzübersicht für SKAP1 Antikörper (N-Term) (ABIN2782452)

Target: SKAP1 (Src Kinase Associated phosphoprotein 1 (SKAP1))

Reaktivität: Human, Ratte, Maus, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SKAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SKAP1 Antikörper

Bindungsspezifität: N-Term

Sequenz: RDHILRGFQQ IKARYYWDFQ PQGGDIGQDS SDDNHSGTLG LSLTSDAPFL

Homologie: Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against SKAP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SKAP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 359 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SKAP1

Target: SKAP1 (Src Kinase Associated phosphoprotein 1 (SKAP1))

Andere Bezeichnung: SKAP1

Hintergrund: SKAP1 Is a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins.
Alias Symbols: SCAP1, SKAP55
Protein Interaction Partner: FAM102A, PRAM1, SH2D4A, BLCAP, APP, LCK, FYN, FYB, SRC, LYN, PTPRC, GRB2, SKAP1,
Protein Size: 359

Molekulargewicht: 41 kDa

Gen-ID: 8631

NCBI Accession: NM_003726, NP_003717

UniProt: Q86WV1