GUCY1B3 Antikörper (N-Term)

Produktnummer ABIN2782430

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GUCY1B3 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio) und Pferd.

Kurzübersicht für GUCY1B3 Antikörper (N-Term) (ABIN2782430)

Target: GUCY1B3 (Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Kaninchen, Zebrafisch (Danio rerio), Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GUCY1B3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GUCY1B3 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: GUCY1B1 Antibody - N-terminal region

Sequenz: LIEEKESKEE DFYEDLDRFE ENGTQESRIS PYTFCKAFPF HIIFDRDLVV

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against GUCY1B3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GUCY1B3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP46012-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GUCY1B3

Target: GUCY1B3 (Guanylate Cyclase 1, Soluble, beta 3 (GUCY1B3))

Andere Bezeichnung: GUCY1B1

Hintergrund:

Targeted Subunit: beta-1

Background Information: This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants.

Gene Name: guanylate cyclase 1 soluble subunit beta 1

Alternative Symbols: GUCB3, GC-SB3, GUC1B3, GUCSB3, GUCY1B3, GC-S-beta-1

Protein Name: guanylate cyclase soluble subunit beta-1

Molekulargewicht: 70kDa

Gen-ID: 2983

NCBI Accession: NP_000848

UniProt: Q02153

Pathways: Transition Metal Ion Homeostasis