SIK1 Antikörper (N-Term)
Kurzübersicht für SIK1 Antikörper (N-Term) (ABIN2782413)
Target
Alle SIK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Sequenz
- MVIMSEFSAD PAGQGQGQQK PLRVGFYDIE RTLGKGNFAV VKLARHRVTK
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Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 90%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against SNF1LK. It was validated on Western Blot and immunohistochemistry.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human SNF1LK
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 783 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SIK1 (Salt-Inducible Kinase 1 (SIK1))
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Andere Bezeichnung
- SNF1LK
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Hintergrund
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SNF1LK play a transient role during the earliest stages of myocardial cell differentiation and/or primitive chamber formation and may also be important for the earliest stages of skeletal muscle growth and/or differentiation. It also plays a potential role in G2/M cell cycle regulation. It inhibits CREB activity by phosphorylating and repressing the CREB-specific coactivators, CRTC1-3.
Alias Symbols: MSK, SIK, SNF1LK
Protein Interaction Partner: TAB2, MAP3K7, HDAC5, UBC, SUPT5H, RPL3, PRKACA, NMNAT1, STK11, ELAVL1, YWHAZ, PRKAA1, CRTC2, VAPA,
Protein Size: 783 -
Molekulargewicht
- 85 kDa
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Gen-ID
- 150094
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NCBI Accession
- NM_173354, NP_775490
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UniProt
- P57059
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
Target
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