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SIK1 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch SIK1 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Pferd, Hund, Meerschweinchen, Rind (Kuh), Schwein und Kaninchen.
Produktnummer ABIN2782413

Kurzübersicht für SIK1 Antikörper (N-Term) (ABIN2782413)

Target

Alle SIK1 Antikörper anzeigen
SIK1 (Salt-Inducible Kinase 1 (SIK1))

Reaktivität

  • 67
  • 34
  • 21
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte, Pferd, Hund, Meerschweinchen, Rind (Kuh), Schwein, Kaninchen

Wirt

  • 67
  • 5
Kaninchen

Klonalität

  • 69
  • 3
Polyklonal

Konjugat

  • 30
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser SIK1 Antikörper ist unkonjugiert

Applikation

  • 51
  • 31
  • 14
  • 14
  • 8
  • 7
  • 2
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 16
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    MVIMSEFSAD PAGQGQGQQK PLRVGFYDIE RTLGKGNFAV VKLARHRVTK

    Homologie

    Cow: 100%, Dog: 93%, Guinea Pig: 85%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 90%, Rat: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against SNF1LK. It was validated on Western Blot and immunohistochemistry.

    Aufreinigung

    Protein A purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human SNF1LK
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 783 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    SIK1 (Salt-Inducible Kinase 1 (SIK1))

    Andere Bezeichnung

    SNF1LK

    Hintergrund

    SNF1LK play a transient role during the earliest stages of myocardial cell differentiation and/or primitive chamber formation and may also be important for the earliest stages of skeletal muscle growth and/or differentiation. It also plays a potential role in G2/M cell cycle regulation. It inhibits CREB activity by phosphorylating and repressing the CREB-specific coactivators, CRTC1-3.
    Alias Symbols: MSK, SIK, SNF1LK
    Protein Interaction Partner: TAB2, MAP3K7, HDAC5, UBC, SUPT5H, RPL3, PRKACA, NMNAT1, STK11, ELAVL1, YWHAZ, PRKAA1, CRTC2, VAPA,
    Protein Size: 783

    Molekulargewicht

    85 kDa

    Gen-ID

    150094

    NCBI Accession

    NM_173354, NP_775490

    UniProt

    P57059

    Pathways

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
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