SIK1 Antikörper (Middle Region)
Kurzübersicht für SIK1 Antikörper (Middle Region) (ABIN2782412)
Target
Alle SIK1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- Middle Region
-
Sequenz
- TPVLQSQAGL GATVLPPVSF QEGRRASDTS LTQGLKAFRQ QLRKNARTKG
-
Homologie
- Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%
-
Produktmerkmale
- This is a rabbit polyclonal antibody against Sik1. It was validated on Western Blot.
-
Aufreinigung
- Affinity Purified
-
-
-
-
Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
-
Kommentare
-
Antigen size: 776 AA
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Handhabung
- Avoid repeated freeze-thaw cycles.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
-
: "The adrenergic-regulated CRTC1 and CRTC2 phosphorylation and cellular distribution is independent of endogenous SIK1 in the male rat pinealocyte." in: Molecular and cellular endocrinology, Vol. 414, pp. 156-67, (2015) (PubMed).
-
: "The adrenergic-regulated CRTC1 and CRTC2 phosphorylation and cellular distribution is independent of endogenous SIK1 in the male rat pinealocyte." in: Molecular and cellular endocrinology, Vol. 414, pp. 156-67, (2015) (PubMed).
-
- SIK1 (Salt-Inducible Kinase 1 (SIK1))
-
Andere Bezeichnung
- Sik1
-
Hintergrund
-
Sik1 inhibits CREB binding and transcription of cAMP-responsive element (CRE)-dependent genes Cyp11A and Star.
Alias Symbols: Sik, Snf1lk
Protein Size: 776 -
Molekulargewicht
- 85 kDa
-
Gen-ID
- 59329
-
NCBI Accession
- NM_021693, NP_067725
-
UniProt
- Q9R1U5
-
Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process
Target
-