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POFUT2 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch POFUT2 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio) und Hund und wurde in 1 Publikation erwähnt.
Produktnummer ABIN2782385

Kurzübersicht für POFUT2 Antikörper (N-Term) (ABIN2782385)

Target

Alle POFUT2 Antikörper anzeigen
POFUT2 (Protein O-Fucosyltransferase 2 (POFUT2))

Reaktivität

  • 30
  • 7
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Zebrafisch (Danio rerio), Hund

Wirt

  • 28
  • 2
Kaninchen

Klonalität

  • 28
  • 2
Polyklonal

Konjugat

  • 21
  • 3
  • 2
  • 2
  • 1
  • 1
Dieser POFUT2 Antikörper ist unkonjugiert

Applikation

  • 22
  • 18
  • 16
  • 4
  • 2
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Sequenz

    GAASRRRYLL YDVNPPEGFN LRRDVYIRIA SLLKTLLKTE EWVLVLPPWG

    Homologie

    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rat: 100%, Zebrafish: 100%

    Produktmerkmale

    This is a rabbit polyclonal antibody against POFUT2. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human POFUT2
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 429 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Luo, Koles, Vorndam, Haltiwanger, Panin: "Protein O-fucosyltransferase 2 adds O-fucose to thrombospondin type 1 repeats." in: The Journal of biological chemistry, Vol. 281, Issue 14, pp. 9393-9, (2006) (PubMed).

  • Target

    POFUT2 (Protein O-Fucosyltransferase 2 (POFUT2))

    Andere Bezeichnung

    POFUT2

    Hintergrund

    POFUT2 catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in thrombospondin type 1 repeats. Fucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O-linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF, MIM 131530)-like repeats or thrombospondin (THBS, see MIM 188060) type-1 repeats. POFUT2 is an O-fucosyltransferase that use THBS type-1 repeats as substrates (Luo et al., 2006 [PubMed 16464857]).[supplied by OMIM].
    Alias Symbols: C21orf80, FUT13
    Protein Interaction Partner: USP22,
    Protein Size: 429

    Molekulargewicht

    50 kDa

    Gen-ID

    23275

    NCBI Accession

    NM_133635, NP_598368

    UniProt

    Q9Y2G5
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