CBR1 Antikörper (Middle Region)

Produktnummer ABIN2782364

Dieser Anti-CBR1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von CBR1 in WB und IHC. Geeignet für Human, Maus, Ratte, Rind (Kuh), Schwein, Kaninchen, Hund, Meerschweinchen, Pferd und Zebrafisch (Danio rerio). Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für CBR1 Antikörper (Middle Region) (ABIN2782364)

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Kaninchen, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CBR1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: AEVTMKTNFF GTRDVCTELL PLIKPQGRVV NVSSIMSVRA LKSCSPELQQ

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 93%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against CBR1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CBR1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 277 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CBR1 Antikörper (ABIN2782364)

Mitani, Ito, Harada, Nakano, Inui, Ashida, Yamaji: "Resveratrol reduces the hypoxia-induced resistance to doxorubicin in breast cancer cells." in: Journal of nutritional science and vitaminology, Vol. 60, Issue 2, pp. 122-8, (2014) (PubMed).

Lim, Shin, Jo, Jyothi, Nguyen, Choi, Kim, Park, Eun, Yoon, Ha, Kim: "Carbonyl reductase 1 is an essential regulator of skeletal muscle differentiation and regeneration." in: The international journal of biochemistry & cell biology, Vol. 45, Issue 8, pp. 1784-93, (2013) (PubMed).

Details zu CBR1

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Andere Bezeichnung: CBR1

Hintergrund: Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues.
Alias Symbols: CBR, hCBR1, SDR21C1
Protein Interaction Partner: MDM2, GRB2, VHL, ESR1, UBC, COPS5, CUL1, UL27, RAD21, Mapk13, UBA5, DDA1, ATG101, PRKAB1, EGFR, ERCC8, MCC,
Protein Size: 277

Molekulargewicht: 30 kDa

Gen-ID: 873

NCBI Accession: NM_001757, NP_001748

UniProt: P16152