CBR1 Antikörper (Middle Region)

Produktnummer ABIN2782364

Dieses Anti-CBR1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CBR1 in WB und IHC. Geeignet für Human, Maus, Ratte, Rind (Kuh), Schwein, Kaninchen, Hund, Meerschweinchen, Pferd und Zebrafisch (Danio rerio). Dieses Primary Antibody wurde in 2+ Publikationen zitiert.

Kurzübersicht für CBR1 Antikörper (Middle Region) (ABIN2782364)

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Schwein, Kaninchen, Hund, Meerschweinchen, Pferd, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CBR1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: AEVTMKTNFF GTRDVCTELL PLIKPQGRVV NVSSIMSVRA LKSCSPELQQ

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 79%, Rat: 93%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against CBR1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CBR1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 277 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CBR1 Antikörper (ABIN2782364)

Mitani, Ito, Harada, Nakano, Inui, Ashida, Yamaji: "Resveratrol reduces the hypoxia-induced resistance to doxorubicin in breast cancer cells." in: Journal of nutritional science and vitaminology, Vol. 60, Issue 2, pp. 122-8, (2014) (PubMed).

Lim, Shin, Jo, Jyothi, Nguyen, Choi, Kim, Park, Eun, Yoon, Ha, Kim: "Carbonyl reductase 1 is an essential regulator of skeletal muscle differentiation and regeneration." in: The international journal of biochemistry & cell biology, Vol. 45, Issue 8, pp. 1784-93, (2013) (PubMed).

Details zu CBR1

Target: CBR1 (Carbonyl Reductase 1 (CBR1))

Andere Bezeichnung: CBR1

Hintergrund: Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues.
Alias Symbols: CBR, hCBR1, SDR21C1
Protein Interaction Partner: MDM2, GRB2, VHL, ESR1, UBC, COPS5, CUL1, UL27, RAD21, Mapk13, UBA5, DDA1, ATG101, PRKAB1, EGFR, ERCC8, MCC,
Protein Size: 277

Molekulargewicht: 30 kDa

Gen-ID: 873

NCBI Accession: NM_001757, NP_001748

UniProt: P16152