UBASH3A Antikörper (Middle Region)
Kurzübersicht für UBASH3A Antikörper (Middle Region) (ABIN2782357)
Target
Alle UBASH3A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- PCSLPRRSRG IKDFENDPPL SSCGIFQSRI AGDALLDSGI RISSVFASPA
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Homologie
- Cow: 100%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 79%, Rat: 93%, Yeast: 82%
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Produktmerkmale
- This is a rabbit polyclonal antibody against UBASH3A. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human UBASH3A
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 661 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- UBASH3A (Ubiquitin Associated and SH3 Domain Containing, A (UBASH3A))
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Andere Bezeichnung
- UBASH3A
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Hintergrund
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UBASH3A interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. It also promotes accumulation of activated target receptors, such as T-cell receptors, EGFR and PDGFRB, on the cell surface.
Alias Symbols: CLIP4, STS-2, TULA, TULA-1
Protein Interaction Partner: KRT40, SF3B4, SPRY2, DAZAP2, TP53BP2, REL, TRIM37, KCNE1, CBS, UBC, CRK, UBASH3B, PARK2, CBL, ABCE1, gag, AIFM1, EGFR, ALK, DNM1, UBB, UBE2L3,
Protein Size: 661 -
Molekulargewicht
- 74 kDa
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Gen-ID
- 53347
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NCBI Accession
- NM_018961, NP_061834
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UniProt
- P57075
Target
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