ALDH4A1 Antikörper (C-Term)

Produktnummer ABIN2782324

Produktdetails anti-ALDH4A1 Antikörper

Target: ALDH4A1 (Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Rind (Kuh), Hund, Pferd, Zebrafisch (Danio rerio), Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ALDH4A1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: RNAAGNFYIN DKSTGSIVGQ QPFGGARASG TNDKPGGPHY ILRWTSPQVI

Homologie: Cow: 100%, Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ALDH4A1. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human ALDH4A1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 563 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ALDH4A1

Target: ALDH4A1 (Aldehyde Dehydrogenase 4 Family, Member A1 (ALDH4A1))

Andere Bezeichnung: ALDH4A1 (ALDH4A1 Produkte)

Synonyme: aldh4 antikoerper, p5cd antikoerper, p5cdh antikoerper, ALDH4 antikoerper, P5CD antikoerper, P5CDh antikoerper, A930035F14Rik antikoerper, Ahd-1 antikoerper, Ahd1 antikoerper, Aldh4 antikoerper, Aldh5a1 antikoerper, E330022C09 antikoerper, P5cd antikoerper, P5cdh antikoerper, P5cdhl antikoerper, P5cdhs antikoerper, Ssdh1 antikoerper, zgc:63592 antikoerper, aldehyde dehydrogenase 4 family member A1 antikoerper, aldehyde dehydrogenase 4 family, member A1 antikoerper, aldehyde dehydrogenase 4 family member A1 L homeolog antikoerper, aldh4a1 antikoerper, ALDH4A1 antikoerper, Aldh4a1 antikoerper, aldh4a1.L antikoerper

Hintergrund: ALDH4A1 belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline.This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Two transcript variants encoding the same protein have been identified for this gene.
Alias Symbols: ALDH4, P5CD, P5CDh, P5CDhL, P5CDhS
Protein Interaction Partner: UBC, MDM2, ALDH4A1, ARG1, APP,
Protein Size: 563

Molekulargewicht: 62 kDa

Gen-ID: 8659

NCBI Accession: NM_003748, NP_003739

UniProt: P30038

Pathways: Monocarboxylic Acid Catabolic Process