HAL Antikörper (C-Term)

Produktnummer ABIN2782321

Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-HAL Antikörper wird verwendet zum Nachweis von HAL in Proben von Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Hund, Meerschweinchen und Pferd. Er wurde validiert für WB und IHC.

Kurzübersicht für HAL Antikörper (C-Term) (ABIN2782321)

Target: HAL (Histidine Ammonia-Lyase (HAL))

Reaktivität: Human, Maus, Ratte, Zebrafisch (Danio rerio), Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HAL Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-HAL Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: HAL Antibody - C-terminal region

Sequenz: EAAHRLLLEQ KVWEVAAPYI EKYRMEHIPE SRPLSPTAFS LQFLHKKSTK

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against HAL. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human HAL

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8102553

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-HAL Antikörper (ABIN2782321)

Hu, Lausted, Yoo, Yan, Brightman, Chen, Wang, Bu, Hood: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).

Alemán, Ortíz, Langley, Tovar, Torres: "Regulation by glucagon of the rat histidase gene promoter in cultured rat hepatocytes and human hepatoblastoma cells." in: American journal of physiology. Endocrinology and metabolism, Vol. 289, Issue 1, pp. E172-9, (2005) (PubMed).

Details zu HAL

Target: HAL (Histidine Ammonia-Lyase (HAL))

Andere Bezeichnung: HAL

Hintergrund:

Background Information: HAL is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. HAL defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluidsHistidine ammonia-lyase is a cytosolic enzyme catalyzing the first reaction in histidine catabolism, the nonoxidative deamination of L-histidine to trans-urocanic acid. Histidine ammonia-lyase defects cause histidinemia which is characterized by increased histidine and histamine and decreased urocanic acid in body fluids.

Gene Name: Histidine ammonia-lyase

Alternative Symbols: HIS, HSTD

Protein Name: Histidine ammonia-lyase

Molekulargewicht: 72kDa

Gen-ID: 3034

NCBI Accession: NP_002099

UniProt: P42357