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DEGS1 Antikörper (N-Term)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DEGS1 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Ziege, Pferd, Kaninchen, Schaf und Zebrafisch (Danio rerio).
Produktnummer ABIN2782243

Kurzübersicht für DEGS1 Antikörper (N-Term) (ABIN2782243)

Target

Alle DEGS1 Antikörper anzeigen
DEGS1 (Sphingolipid Delta(4)-Desaturase DES1 (DEGS1))

Reaktivität

Human, Maus, Ratte, Meerschweinchen, Rind (Kuh), Ziege, Pferd, Kaninchen, Schaf, Zebrafisch (Danio rerio)

Wirt

  • 36
  • 2
Kaninchen

Klonalität

  • 35
  • 3
Polyklonal

Konjugat

  • 12
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DEGS1 Antikörper ist unkonjugiert

Applikation

  • 14
  • 14
  • 13
  • 13
  • 10
  • 5
  • 3
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 15
    • 8
    • 3
    • 2
    • 1
    N-Term

    Sequenz

    GSRVSREDFE WVYTDQPHAD RRREILAKYP EIKSLMKPDP NLIWIIIMMV

    Homologie

    Cow: 100%, Goat: 86%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 93%, Zebrafish: 93%

    Produktmerkmale

    This is a rabbit polyclonal antibody against DEGS1. It was validated on Western Blot using a cell lysate as a positive control.

    Aufreinigung

    Affinity Purified

    Immunogen

    The immunogen is a synthetic peptide directed towards the N terminal region of human DEGS1
  • Applikationshinweise

    Optimal working dilutions should be determined experimentally by the investigator.

    Kommentare

    Antigen size: 323 AA

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    Lot specific

    Buffer

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handhabung

    Avoid repeated freeze-thaw cycles.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target

    DEGS1 (Sphingolipid Delta(4)-Desaturase DES1 (DEGS1))

    Andere Bezeichnung

    DEGS1

    Hintergrund

    DEGS1 is a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this protein inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified.
    Alias Symbols: DEGS, DES1, Des-1, FADS7, MGC5079, MIG15, MLD, DEGS-1
    Protein Interaction Partner: UBC, NAGPA, UBD, EGFR, TSSC1, SURF4, SLC16A1, PYGM,
    Protein Size: 323

    Molekulargewicht

    38 kDa

    Gen-ID

    8560

    NCBI Accession

    NM_003676, NP_003667

    UniProt

    O15121
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