CNTNAP1 Antikörper (N-Term)

Produktnummer ABIN2782237

Der Kaninchen Polyklonal Anti-CNTNAP1-Antikörper wurde für WB validiert. Er ist geeignet, CNTNAP1 in Proben von Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd und Kaninchen zu detektieren.

Kurzübersicht für CNTNAP1 Antikörper (N-Term) (ABIN2782237)

Target: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNTNAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CNTNAP1 Antikörper

Bindungsspezifität: N-Term

Sequenz: LQIDLMKKHR IRAVATQGSF NSWDWVTRYM LLYGDRVDSW TPFYQRGHNS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CNTNAP1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CNTNAP1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1384 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu CNTNAP1

Target: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Andere Bezeichnung: CNTNAP1

Hintergrund: CNTNAP1 was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,381-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.
Alias Symbols: CASPR, CNTNAP, NRXN4, P190
Protein Interaction Partner: UBC, vpu, FBXO6, NFASC, RTN4, SRC, PTPRB, RHOA, FYN, RAC1, CDC42, KCNA1, KCNA2,
Protein Size: 1384

Molekulargewicht: 156 kDa

Gen-ID: 8506

NCBI Accession: NM_003632, NP_003623

UniProt: P78357

Pathways: Cell-Cell Junction Organization