PI3 Antikörper (Middle Region)
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- Target Alle PI3 Antikörper anzeigen
- PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Rind (Kuh), Schwein, Schaf
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PI3 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- KGRVPFNGQD PVKGQVSVKG QDKVKAQEPV KGPVSTKPGS CPIILIRCAM
- Homologie
- Cow: 85%, Human: 100%, Pig: 77%, Sheep: 77%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PI3. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PI3
- Top Product
- Discover our top product PI3 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 117 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))
- Andere Bezeichnung
- PI3 (PI3 Produkte)
- Synonyme
- ESI antikoerper, SKALP antikoerper, WAP3 antikoerper, WFDC14 antikoerper, cementoin antikoerper, trappin-2 antikoerper, TRAPPIN-2 antikoerper, elafin antikoerper, peptidase inhibitor 3 antikoerper, peptidase inhibitor 3, skin-derived (SKALP) antikoerper, PI3 antikoerper
- Hintergrund
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PI3 is an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. PI3 contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. PI3 belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.This gene encodes an elastase-specific inhibitor, which contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ESI, MGC13613, SKALP, WAP3, WFDC14, cementoin
Protein Interaction Partner: EVPL, CELA1, LOR, KRT1, CSTA,
Protein Size: 117 - Molekulargewicht
- 6 kDa
- Gen-ID
- 5266
- NCBI Accession
- NM_002638, NP_002629
- UniProt
- P19957
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