PI3 Antikörper (N-Term)

Produktnummer ABIN2782186

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch PI3 in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für PI3 Antikörper (N-Term) (ABIN2782186)

Target: PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PI3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PI3 Antikörper

Bindungsspezifität: N-Term

Sequenz: RASSFLIVVV FLIAGTLVLE AAVTGVPVKG QDTVKGRVPF NGQDPVKGQV

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PI3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human PI3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 117 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PI3

Target: PI3 (Peptidase Inhibitor 3, Skin-Derived (PI3))

Andere Bezeichnung: PI3

Hintergrund: PI3 is an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria. PI3 contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. PI3 belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.This gene encodes an elastase-specific inhibitor, which contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: ESI, MGC13613, SKALP, WAP3, WFDC14, cementoin
Protein Interaction Partner: EVPL, CELA1, LOR, KRT1, CSTA,
Protein Size: 117

Molekulargewicht: 6 kDa

Gen-ID: 5266

NCBI Accession: NM_002638, NP_002629

UniProt: P19957