Protocadherin 8 Antikörper (Middle Region)

Produktnummer ABIN2782184

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Protocadherin 8 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen und Rind (Kuh).

Kurzübersicht für Protocadherin 8 Antikörper (Middle Region) (ABIN2782184)

Target: Protocadherin 8 (PCDH8)

Reaktivität: Human, Maus, Ratte, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Protocadherin 8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Protocadherin 8 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: PCDH8 Antibody - middle region

Sequenz: GATSLVPEGA ARESLVALVS TSDRDSGANG QVRCALYGHE HFRLQPAYAG

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PCDH8. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PCDH8

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45338-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Protocadherin 8

Target: Protocadherin 8 (PCDH8)

Andere Bezeichnung: PCDH8

Hintergrund:

Background Information: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. PCDH8 is an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region.This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner. Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons. Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region. Alternative splicing yields isoforms with unique cytoplasmic tails.

Gene Name: Protocadherin 8

Alternative Symbols: PAPC, ARCADLIN

Protein Name: Protocadherin-8

Molekulargewicht: 101kDa

Gen-ID: 5100

NCBI Accession: NP_116567

UniProt: Q5TAN1