Lamin B Receptor Antikörper (Middle Region)

Produktnummer ABIN2782167

Der Kaninchen Polyklonal anti-Lamin B Receptor Antikörper wird verwendet zum Nachweis von Lamin B Receptor in Proben von Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio), Hund, Pferd, Schwein, Kaninchen und Saccharomyces cerevisiae. Er wurde validiert für WB und IP.

Kurzübersicht für Lamin B Receptor Antikörper (Middle Region) (ABIN2782167)

Target: Lamin B Receptor (LBR)

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Meerschweinchen, Zebrafisch (Danio rerio), Hund, Pferd, Schwein, Kaninchen, Saccharomyces cerevisiae

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Lamin B Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP)

Produktdetails anti-Lamin B Receptor Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: LBR Antibody - middle region

Sequenz: GANSQKNAFR KNPSDPKLAH LKTIHTSTGK NLLVSGWWGF VRHPNYLGDL

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 100%, Yeast: 77%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against LBR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LBR

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45263-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Lamin B Receptor

Target: Lamin B Receptor (LBR)

Andere Bezeichnung: LBR

Hintergrund:

Background Information: The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified.

Gene Name: Lamin B receptor

Alternative Symbols: PHA, C14SR, LMN2R, PHASK, TDRD18, DHCR14B

Protein Name: Lamin-B receptor

Molekulargewicht: 71kDa

Gen-ID: 3930

NCBI Accession: NP_002287

UniProt: Q14739