JAG2 Antikörper (N-Term)

Produktnummer ABIN2782165

Produktdetails anti-JAG2 Antikörper

Target: JAG2 (Jagged 2 (JAG2))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JAG2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: RAQGRGRLPR RLLLLLALWV QAARPMGYFE LQLSALRNVN GELLSGACCD

Homologie: Human: 100%, Mouse: 100%, Pig: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against JAG2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human JAG2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1238 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-JAG2 Antikörper (ABIN2782165)

Passos Gregorio, Gattaz, Tavares, Kieling, Timm, Wang, Berg Rasmussen, Werge, Dias-Neto: "Analysis of coding-polymorphisms in NOTCH-related genes reveals NUMBL poly-glutamine repeat to be associated with schizophrenia in Brazilian and Danish subjects." in: Schizophrenia research, Vol. 88, Issue 1-3, pp. 275-82, (2006) (PubMed).

Details zu JAG2

Target: JAG2 (Jagged 2 (JAG2))

Andere Bezeichnung: JAG2 (JAG2 Produkte)

Synonyme: D12Ggc2e antikoerper, Serh antikoerper, mJagged2-1 antikoerper, sm antikoerper, HJ2 antikoerper, SER2 antikoerper, jag2 antikoerper, serB antikoerper, zgc:152855 antikoerper, jagged 2 antikoerper, jagged 2b antikoerper, JAG2 antikoerper, jag2 antikoerper, Jag2 antikoerper, jag2b antikoerper

Hintergrund: The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch protein family are transmembrane receptors that are critical for various cell fate decisions. JAG2 is one of several ligands that activate Notch and related receptors. The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. The protein encoded by this gene is one of several ligands that activate Notch and related receptors. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: HJ2, SER2
Protein Interaction Partner: GFI1B, ATN1, ATXN7, CACNA1A, MIB2, NOTCH3, NOTCH2, NOTCH1,
Protein Size: 1238

Molekulargewicht: 130 kDa

Gen-ID: 3714

NCBI Accession: NM_002226, NP_002217

UniProt: Q9Y219

Pathways: Notch Signalweg, Sensory Perception of Sound