GZMK Antikörper (N-Term)
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- Target Alle GZMK Antikörper anzeigen
- GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))
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Bindungsspezifität
- N-Term
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Reaktivität
- Human, Schwein, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GZMK Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- PTVVLGAHSL SKNEASKQTL EIKKFIPFSR VTSDPQSNDI MLVKLQTAAK
- Homologie
- Horse: 79%, Human: 100%, Pig: 86%
- Produktmerkmale
- This is a rabbit polyclonal antibody against GZMK. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the N terminal region of human GZMK
- Top Product
- Discover our top product GZMK Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 264 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))
- Andere Bezeichnung
- GZMK (GZMK Produkte)
- Synonyme
- TRYP2 antikoerper, granzyme K antikoerper, GZMK antikoerper, Gzmk antikoerper
- Hintergrund
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GZMK is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.
Alias Symbols: TRYP2
Protein Interaction Partner: SET, HMGB2, APEX1, PNKP, LIG4, HNRNPK, GOLGA2, ACTG1, TUBB3, NPLOC4, VCP, UFD1L,
Protein Size: 264 - Molekulargewicht
- 26 kDa
- Gen-ID
- 3003
- NCBI Accession
- NM_002104, NP_002095
- UniProt
- P49863
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