GZMK Antikörper (N-Term)

Produktnummer ABIN2782156

Der Kaninchen Polyklonal anti-GZMK Antikörper wird verwendet zum Nachweis von GZMK in Proben von Human, Schwein und Pferd. Er wurde validiert für WB.

Kurzübersicht für GZMK Antikörper (N-Term) (ABIN2782156)

Target: GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Reaktivität: Human, Schwein, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GZMK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GZMK Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: GZMK Antibody - N-terminal region

Sequenz: PTVVLGAHSL SKNEASKQTL EIKKFIPFSR VTSDPQSNDI MLVKLQTAAK

Homologie: Horse: 79%, Human: 100%, Pig: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against GZMK. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GZMK

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8101902

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GZMK

Target: GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Andere Bezeichnung: GZMK

Hintergrund:

Background Information: GZMK is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.

Gene Name: Granzyme K (granzyme 3, tryptase II)

Alternative Symbols: TRYP2

Protein Name: Granzyme K

Molekulargewicht: 26kDa

Gen-ID: 3003

NCBI Accession: NP_002095

UniProt: P49863