GZMK Antikörper (N-Term)

Produktnummer ABIN2782156

Der Kaninchen Polyklonal Anti-GZMK-Antikörper wurde für WB validiert. Er ist geeignet, GZMK in Proben von Human, Schwein und Pferd zu detektieren.

Kurzübersicht für GZMK Antikörper (N-Term) (ABIN2782156)

Target: GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Reaktivität: Human, Schwein, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GZMK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GZMK Antikörper

Bindungsspezifität: N-Term

Sequenz: PTVVLGAHSL SKNEASKQTL EIKKFIPFSR VTSDPQSNDI MLVKLQTAAK

Homologie: Horse: 79%, Human: 100%, Pig: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against GZMK. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human GZMK

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 264 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GZMK

Target: GZMK (Granzyme K (Granzyme 3, Tryptase II) (GZMK))

Andere Bezeichnung: GZMK

Hintergrund: GZMK is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.This gene product is a member of a group of related serine proteases from the cytoplasmic granules of cytotoxic lymphocytes. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here lacks consensus sequences for N-glycosylation present in other granzymes.
Alias Symbols: TRYP2
Protein Interaction Partner: SET, HMGB2, APEX1, PNKP, LIG4, HNRNPK, GOLGA2, ACTG1, TUBB3, NPLOC4, VCP, UFD1L,
Protein Size: 264

Molekulargewicht: 26 kDa

Gen-ID: 3003

NCBI Accession: NM_002104, NP_002095

UniProt: P49863