FVT1 Antikörper (N-Term)

Produktnummer ABIN2782154

Produktdetails anti-FVT1 Antikörper

Target: FVT1 (KDSR) (3-Ketodihydrosphingosine Reductase (KDSR))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Rind (Kuh), Hund, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FVT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: KKEIEMHSIN DKQVVLCISV DVSQDYNQVE NVIKQAQEKL GPVDMLVNCA

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against KDSR. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of human KDSR

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FVT1

Target: FVT1 (KDSR) (3-Ketodihydrosphingosine Reductase (KDSR))

Andere Bezeichnung: KDSR (KDSR Produkte)

Hintergrund: The protein encoded by this gene catalyzes the reduction of 3-ketodihydrosphingosine to dihydrosphingosine. The putative active site residues of the encoded protein are found on the cytosolic side of the endoplasmic reticulum membrane. A chromosomal rearrangement involving this gene is a cause of follicular lymphoma, also known as type II chronic lymphatic leukemia. The mutation of a conserved residue in the bovine ortholog causes spinal muscular atrophy.
Alias Symbols: DHSR, FVT1, SDR35C1
Protein Size: 268

Molekulargewicht: 29 kDa

Gen-ID: 2531

NCBI Accession: NM_002035, NP_002026

UniProt: B4DMX0