Desmocollin 3 Antikörper (N-Term)

Produktnummer ABIN2782146

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Desmocollin 3 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein und Kaninchen.

Kurzübersicht für Desmocollin 3 Antikörper (N-Term) (ABIN2782146)

Target: Desmocollin 3 (DSC3)

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Desmocollin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Desmocollin 3 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: DSC3 Antibody - N-terminal region

Sequenz: MQENSLGPFP LFLQQVESDA AQNYTVFYSI SGRGVDKEPL NLFYIERDTG

Homologie: Cow: 100%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 86%, Pig: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against DSC3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human DSC3

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45195-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu Desmocollin 3

Target: Desmocollin 3 (DSC3)

Andere Bezeichnung: DSC3

Hintergrund:

Background Information: DSC3 is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.The protein encoded by this gene is a calcium-dependent glycoprotein that is a member of the desmocollin subfamily of the cadherin superfamily. These desmosomal family members, along with the desmogleins, are found primarily in epithelial cells where they constitute the adhesive proteins of the desmosome cell-cell junction and are required for cell adhesion and desmosome formation. The desmosomal family members are arranged in two clusters on chromosome 18, occupying less than 650 kb combined. Alternative splicing results in two transcript variants encoding distinct isoforms.

Gene Name: Desmocollin 3

Alternative Symbols: DSC, DSC1, DSC2, DSC4, CDHF3, HT-CP

Protein Name: Desmocollin-3

Molekulargewicht: 85kDa

Gen-ID: 1825

NCBI Accession: NP_001932

UniProt: Q14574