P-Cadherin Antikörper (N-Term)

Produktnummer ABIN2782138

Produktdetails anti-P-Cadherin Antikörper

Target: P-Cadherin (CDH3)

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Schwein, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser P-Cadherin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: AVSENGASVE DPMNISIIVT DQNDHKPKFT QDTFRGSVLE GVLPGTSVMQ

Homologie: Cow: 93%, Dog: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Pig: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against CDH3. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human CDH3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 829 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu P-Cadherin

Target: P-Cadherin (CDH3)

Andere Bezeichnung: CDH3 (CDH3 Produkte)

Synonyme: CDH3 antikoerper, Cadherin-3 antikoerper, AI385538 antikoerper, Cadp antikoerper, Cdhp antikoerper, P-cadherin antikoerper, Pcad antikoerper, CDHP antikoerper, HJMD antikoerper, PCAD antikoerper, E-Cad antikoerper, E-cadherin antikoerper, EP-cadherin antikoerper, XTCAD-1 antikoerper, c-cadherin antikoerper, cadherin-1 antikoerper, cdh1 antikoerper, cdh1-b antikoerper, cdh3 antikoerper, cdhc-A antikoerper, cdhp antikoerper, hjmd antikoerper, l-cam antikoerper, lcam antikoerper, pcad antikoerper, uvo antikoerper, uvomorulin antikoerper, xb-cad antikoerper, xcdh1 antikoerper, CDH15 antikoerper, K-CAM antikoerper, cadherin 3 antikoerper, cadherin 3 L homeolog antikoerper, Cadherin-3 antikoerper, CDH3 antikoerper, Cdh3 antikoerper, cdh3.L antikoerper, cdh-3 antikoerper

Hintergrund: CDH3 is a classical cadherin from the cadherin superfamily. The protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Its gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in its gene have been associated with congential hypotrichosis with juvenile macular dystrophy.This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.
Alias Symbols: CDHP, HJMD, PCAD
Protein Interaction Partner: UBC, CTNND1, CTNNB1, CTNNA1, CDH3, JUP, CDH1,
Protein Size: 829

Molekulargewicht: 91 kDa

Gen-ID: 1001

NCBI Accession: NM_001793, NP_001784

UniProt: P22223