B4GALNT1 Antikörper (Middle Region)
Kurzübersicht für B4GALNT1 Antikörper (Middle Region) (ABIN2782130)
Target
Alle B4GALNT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Verwendungszweck
- B4GALNT1 Antibody - middle region
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Sequenz
- GLGSLRVGSC SDVVVDHASK LKLPWTSRDA GAETYARYRY PGSLDESQMA
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Homologie
- Cow: 100%, Dog: 100%, Guinea Pig: 92%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%
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Produktmerkmale
- This is a rabbit polyclonal antibody against B4GALNT1. It was validated on Western Blot using a cell lysate as a positive control.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human B4GALNT1
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Kommentare
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45118-100UG
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- prevent freeze-thaw cycles
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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: "Diversity of glycosphingolipid GM2 and cholesterol accumulation in NPC1 patient-specific iPSC-derived neurons." in: Brain research, Vol. 1657, pp. 52-61, (2016) (PubMed).
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- B4GALNT1 (beta-1,4-N-Acetyl-Galactosaminyl Transferase 1 (B4GALNT1))
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Andere Bezeichnung
- B4GALNT1
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Hintergrund
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Background Information: GM2 and GD2 gangliosides are sialic acid-containing glycosphingolipids. GalNAc-T is the enzyme involved in the biosynthesis of G(M2) and G(D2) glycosphingolipids. B4GALNT1(GalNAc-T) catalyzes the transfer of GalNAc into G(M3) and G(D3) by a beta-1,4 linkage, resulting in the synthesis of G(M2) and G(D2), respectively.
Gene Name: Beta-1,4-N-acetyl-galactosaminyl transferase 1
Alternative Symbols: GALGT, SPG26, GALNACT, GalNAc-T
Protein Name: Beta-1,4 N-acetylgalactosaminyltransferase 1
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Molekulargewicht
- 59kDa
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Gen-ID
- 2583
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NCBI Accession
- NP_001469
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UniProt
- Q00973
Target
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