ENPP2 Antikörper (N-Term)

Produktnummer ABIN2782062

Der Kaninchen Polyklonal anti-ENPP2 Antikörper (ABIN2782062) detektiert spezifisch ENPP2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Hund, Meerschweinchen, Pferd, Kaninchen und Rind (Kuh).

Kurzübersicht für ENPP2 Antikörper (N-Term) (ABIN2782062)

Target: ENPP2 (Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))

Reaktivität: Human, Ratte, Maus, Hund, Meerschweinchen, Pferd, Kaninchen, Rind (Kuh)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ENPP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-ENPP2 Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: ENPP2 Antibody - N-terminal region

Sequenz: YTLATGLYPE SHGIVGNSMY DPVFDATFHL RGREKFNHRW WGGQPLWITA

Homologie: Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against ENPP2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ENPP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44907-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu ENPP2

Target: ENPP2 (Ectonucleotide Pyrophosphatase / phosphodiesterase 2 (ENPP2))

Andere Bezeichnung: ENPP2

Hintergrund:

Background Information: The protein encoded by this gene functions as both a phosphodiesterase, which cleaves phosphodiester bonds at the 5' end of oligonucleotides, and a phospholipase, which catalyzes production of lysophosphatidic acid (LPA) in extracellular fluids. LPA evokes growth factor-like responses including stimulation of cell proliferation and chemotaxis. This gene product stimulates the motility of tumor cells and has angiogenic properties, and its expression is upregulated in several kinds of carcinomas. The gene product is secreted and further processed to make the biologically active form. Several alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: Ectonucleotide pyrophosphatase/phosphodiesterase 2

Alternative Symbols: ATX, NPP2, ATX-X, PDNP2, LysoPLD, AUTOTAXIN, PD-IALPHA

Protein Name: Ectonucleotide pyrophosphatase/phosphodiesterase family member 2

Molekulargewicht: 99 kDa

Gen-ID: 5168

NCBI Accession: NP_001035181

UniProt: Q13822