AGPAT2 Antikörper (C-Term)

Produktnummer ABIN2781951

Der Kaninchen Polyklonal anti-AGPAT2 Antikörper wird verwendet zum Nachweis von AGPAT2 in Proben von Human und Schwein. Er wurde validiert für WB.

Kurzübersicht für AGPAT2 Antikörper (C-Term) (ABIN2781951)

Target: AGPAT2 (1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (Lysophosphatidic Acid Acyltransferase, Beta) (AGPAT2))

Reaktivität: Human, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AGPAT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-AGPAT2 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: AGPAT2 Antibody - C-terminal region

Sequenz: LEAIPTSGLT AADVPALVDT CHRAMRTTFL HISKTPQENG ATAGSGVQPA

Homologie: Human: 100%, Pig: 91%

Produktmerkmale: This is a rabbit polyclonal antibody against AGPAT2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AGPAT2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8093566

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1.0 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu AGPAT2

Target: AGPAT2 (1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (Lysophosphatidic Acid Acyltransferase, Beta) (AGPAT2))

Andere Bezeichnung: AGPAT2

Hintergrund:

Background Information: AGPAT2 is a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in its gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance.This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Name: 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)

Alternative Symbols: BSCL, BSCL1, LPAAB, 1-AGPAT2, LPAAT-beta

Protein Name: 1-acyl-sn-glycerol-3-phosphate acyltransferase beta

Molekulargewicht: 27kDa

Gen-ID: 10555

NCBI Accession: NP_001012745

UniProt: Q5VUD3