LCLAT1 Antikörper (Middle Region)

Produktnummer ABIN502511

Es gibt 1 Publikation für dieses Produkt. Der Kaninchen Polyklonal anti-LCLAT1 Antikörper wird verwendet zum Nachweis von LCLAT1 in Proben von Human, Maus, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd und Ratte. Er wurde validiert für WB.

Kurzübersicht für LCLAT1 Antikörper (Middle Region) (ABIN502511)

Target: LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))

Reaktivität: Human, Maus, Kaninchen, Rind (Kuh), Hund, Meerschweinchen, Pferd, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LCLAT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-LCLAT1 Antikörper

Bindungsspezifität: Middle Region

Verwendungszweck: LYCAT Antibody - middle region

Sequenz: YLYSLVKWYF IITIVIFVLQ ERIFGGLEII ELACYRLLHK QPHLNSKKNE

Homologie: Cow: 93%, Dog: 92%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%

Produktmerkmale: This is a rabbit polyclonal antibody against LYCAT. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human LYCAT

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP44426-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-LCLAT1 Antikörper (ABIN502511)

Zou, Synan, Li, Xiong, Manni, Liu, Chen, Zhao, Shiva, Tyurina, Jiang, Lee, Das, Ray, Ray, Kagan, Mallampalli: "LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1." in: Journal of cell science, Vol. 129, Issue 1, pp. 51-64, (2016) (PubMed).

Details zu LCLAT1

Target: LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))

Andere Bezeichnung: LYCAT

Hintergrund:

Background Information: LYCAT is an acyl-CoA:lysocardiolipin acyltransferase. It possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. LYCAT recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. LYCAT acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. It converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. LYCAT is required for establishment of the hematopoietic and endothelial lineages.

Gene Name: Lysocardiolipin acyltransferase 1

Alternative Symbols: LYCAT, AGPAT8, ALCAT1, 1AGPAT8, UNQ1849, HSRG1849

Protein Name: cDNA FLJ61482, highly similar to Homo sapiens lysocardiolipin acyltransferase (LYCAT), transcript variant 1, mRNA EMBL BAG63827.1

Molekulargewicht: 44kDa

Gen-ID: 253558

NCBI Accession: NP_001002257

UniProt: Q6UWP7