LCLAT1 Antikörper (Middle Region)
Kurzübersicht für LCLAT1 Antikörper (Middle Region) (ABIN2781857)
Target
Alle LCLAT1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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                                            Bindungsspezifität
- Middle Region
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                                            Sequenz
- YLYSLVKWYF IITIVIFVLQ ERIFGGLEII ELACYRLLHK QPHLNSKKNE
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                                            Homologie
- Cow: 93%, Dog: 92%, Guinea Pig: 92%, Horse: 93%, Human: 100%, Mouse: 92%, Rabbit: 100%, Rat: 92%
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                                            Produktmerkmale
- This is a rabbit polyclonal antibody against LYCAT. It was validated on Western Blot using a cell lysate as a positive control.
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                                            Aufreinigung
- Affinity Purified
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                                            Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human LYCAT
 
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                                            Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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                                            Kommentare
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                        Antigen size: 376 AA 
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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                                            Format
- Liquid
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                                            Konzentration
- Lot specific
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                                            Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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                                            Konservierungsmittel
- Sodium azide
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                                            Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Handhabung
- Avoid repeated freeze-thaw cycles.
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                                            Lagerung
- -20 °C
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                                            Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
 
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    - 
                                            : "LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1."    in: Journal of cell science, Vol. 129, Issue 1, pp. 51-64, (2016)         (PubMed).        
 
 
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                                            : "LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1."    in: Journal of cell science, Vol. 129, Issue 1, pp. 51-64, (2016)         (PubMed).        
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    - LCLAT1 (Lysocardiolipin Acyltransferase 1 (LCLAT1))
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                                            Andere Bezeichnung
- LYCAT
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                                            Hintergrund
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                        LYCAT is an acyl-CoA:lysocardiolipin acyltransferase. It possesses both lysophosphatidylinositol acyltransferase (LPIAT) and lysophosphatidylglycerol acyltransferase (LPGAT) activities. LYCAT recognizes both monolysocardiolipin and dilysocardiolipin as substrates with a preference for linoleoyl-CoA and oleoyl-CoA as acyl donors. LYCAT acts as a remodeling enzyme for cardiolipin, a major membrane polyglycerophospholipid. It converts lysophosphatidic acid (LPA) into phosphatidic acid (PA) with a relatively low activity. LYCAT is required for establishment of the hematopoietic and endothelial lineages.
 Alias Symbols: ALCAT1, FLJ37965, UNQ1849, LYCAT, AGPAT8, 1AGPAT8, HSRG1849
 Protein Interaction Partner: LNX1, GOPC, RNF2, UBC, ELAVL1,
 Protein Size: 376
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                                            Molekulargewicht
- 44 kDa
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                                            Gen-ID
- 253558
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                                            NCBI Accession
- NM_001002257, NP_001002257
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                                            UniProt
- Q6UWP7
 Target
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