PPIB Antikörper (Middle Region)

Produktnummer ABIN310593

Produktdetails anti-PPIB Antikörper

Target: PPIB (Cyclophilin B (PPIB))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Pferd, Meerschweinchen, Zebrafisch (Danio rerio), Kaninchen, Schaf

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPIB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: FITTVKTAWL DGKHVVFGKV LEGMEVVRKV ESTKTDSRDK PLKDVIIADC

Homologie: Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Sheep: 86%, Zebrafish: 79%

Produktmerkmale: This is a rabbit polyclonal antibody against PPIB. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PPIB

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 216 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PPIB

Target: PPIB (Cyclophilin B (PPIB))

Andere Bezeichnung: PPIB (PPIB Produkte)

Hintergrund: PPIB is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression.
Alias Symbols: CYP-S1, CYPB, MGC14109, MGC2224, SCYLP, OI9
Protein Interaction Partner: BANP, UBQLN1, SGTA, PEX19, UBC, MDM2, DDIT3, WWOX, SUZ12, EED, BMI1, rev, RRM1, PPP5C, PFKP, GAPDH, HECW2, FBXO6, UBD, CFTR, ATP12A, VKORC1, OS9, MAGT1, SUGP1, LSM4, TIMM44, SCO2, ZC3H11A, UBL4A, RBMS1, RANGAP1, PCBP2, P4HB, HSPA5, PDIA3, DHX9, ACAA1, MRP
Protein Size: 216

Molekulargewicht: 24 kDa

Gen-ID: 5479

NCBI Accession: NM_000942, NP_000933

UniProt: A8K534