PPIB Antikörper (Middle Region)
Kurzübersicht für PPIB Antikörper (Middle Region) (ABIN2781832)
Target
Alle PPIB Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- FITTVKTAWL DGKHVVFGKV LEGMEVVRKV ESTKTDSRDK PLKDVIIADC
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Homologie
- Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 93%, Sheep: 86%, Zebrafish: 79%
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Produktmerkmale
- This is a rabbit polyclonal antibody against PPIB. It was validated on Western Blot and immunohistochemistry.
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Aufreinigung
- Protein A purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PPIB
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 216 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- PPIB (Cyclophilin B (PPIB))
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Andere Bezeichnung
- PPIB
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Hintergrund
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PPIB is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Western blots using two different antibodies against two unique regions of this protein target confirm the same apparent molecular weight in our tests.The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression.
Alias Symbols: CYP-S1, CYPB, MGC14109, MGC2224, SCYLP, OI9
Protein Interaction Partner: BANP, UBQLN1, SGTA, PEX19, UBC, MDM2, DDIT3, WWOX, SUZ12, EED, BMI1, rev, RRM1, PPP5C, PFKP, GAPDH, HECW2, FBXO6, UBD, CFTR, ATP12A, VKORC1, OS9, MAGT1, SUGP1, LSM4, TIMM44, SCO2, ZC3H11A, UBL4A, RBMS1, RANGAP1, PCBP2, P4HB, HSPA5, PDIA3, DHX9, ACAA1, MRP
Protein Size: 216 -
Molekulargewicht
- 24 kDa
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Gen-ID
- 5479
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NCBI Accession
- NM_000942, NP_000933
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UniProt
- A8K534
Target
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