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HFE Antikörper (N-Term)

HFE Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2781799
  • Target Alle HFE Antikörper anzeigen
    HFE (Hemochromatosis (HFE))
    Bindungsspezifität
    • 16
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 47
    • 8
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen
    Wirt
    • 42
    • 6
    Kaninchen
    Klonalität
    • 43
    • 5
    Polyklonal
    Konjugat
    • 25
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HFE Antikörper ist unkonjugiert
    Applikation
    • 42
    • 20
    • 15
    • 13
    • 13
    • 6
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    MGASEQDLGL SLFEALGYVD DQLFVFYDHE SRRVEPRTPW VSSRISSQMW
    Homologie
    Cow: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 79%, Rat: 79%
    Produktmerkmale
    This is a rabbit polyclonal antibody against HFE. It was validated on Western Blot using a cell lysate as a positive control.
    Aufreinigung
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human HFE
    Top Product
    Discover our top product HFE Primärantikörper
  • Applikationshinweise
    Optimal working dilutions should be determined experimentally by the investigator.
    Kommentare

    Antigen size: 348 AA

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    HFE (Hemochromatosis (HFE))
    Andere Bezeichnung
    HFE (HFE Produkte)
    Synonyme
    HFE1 antikoerper, HH antikoerper, HLA-H antikoerper, MVCD7 antikoerper, TFQTL2 antikoerper, MR2 antikoerper, hemochromatosis antikoerper, HFE antikoerper, Hfe antikoerper
    Hintergrund
    HFE is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in its gene.
    Alias Symbols: HFE1, HH, HLA-H, MGC103790, dJ221C16.10.1, MVCD7, TFQTL2
    Protein Interaction Partner: B2M, SYVN1, UBC, TFR2, TFRC,
    Protein Size: 348
    Molekulargewicht
    40 kDa
    Gen-ID
    3077
    NCBI Accession
    NM_000410, NP_000401
    UniProt
    Q30201
    Pathways
    Transition Metal Ion Homeostasis, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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