NAT2 Antikörper (Middle Region)

Produktnummer ABIN2781757

Produktdetails anti-NAT2 Antikörper

Target: NAT2 (N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAT2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CLTEERGIWY LDQIRREQYI TNKEFLNSHL LPKKKHQKIY LFTLEPRTIE

Spezifität: Antibody reacts with both NAT1 and NAT2

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against NAT2. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NAT2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 290 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-NAT2 Antikörper (ABIN2781757)

Ricco, Cau, Marchand, Marty, Rodde-Dunet, Fender, Allemand, Corsini: "Stent-graft repair for thoracic aortic disease: results of an independent nationwide study in France from 1999 to 2001." in: The Journal of thoracic and cardiovascular surgery, Vol. 131, Issue 1, pp. 131-7, (2006) (PubMed).

Details zu NAT2

Target: NAT2 (N-Acetyltransferase 2 (Arylamine N-Acetyltransferase) (NAT2))

Andere Bezeichnung: NAT2 (NAT2 Produkte)

Synonyme: AAC2 antikoerper, NAT-2 antikoerper, PNAT antikoerper, AV377607 antikoerper, Nat2a antikoerper, NAT antikoerper, AT-2 antikoerper, AT-B/AT-II antikoerper, AT-II antikoerper, AT2 antikoerper, N-acetyltransferase 2 antikoerper, N-acetyltransferase 2 (arylamine N-acetyltransferase) antikoerper, NAT2 antikoerper, Nat2 antikoerper

Hintergrund: NAT2 is a N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in its gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity.This gene encodes N-acetyltransferase 2 (arylamine N-acetyltransferase 2). This enzyme functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are reponsible for the N-acetylation polymorphism in which human populations segregate into rapid,intermediate, and slow acetylator phenotypes. Polymorphisms in NAT2 are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near NAT2.
Alias Symbols: AAC2, PNAT
Protein Interaction Partner: APP, NAA10,
Protein Size: 290

Molekulargewicht: 32 kDa

Gen-ID: 10

NCBI Accession: NM_000015, NP_000006

UniProt: P11245