NHE7 Antikörper (N-Term)

Produktnummer ABIN2781699

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch NHE7 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus, Kaninchen, Meerschweinchen, Hund, Zebrafisch (Danio rerio) und Ziege.

Kurzübersicht für NHE7 Antikörper (N-Term) (ABIN2781699)

Target: NHE7 (SLC9A7) (Sodium Hydrogen Exchanger 7 (SLC9A7))

Reaktivität: Human, Maus, Kaninchen, Meerschweinchen, Hund, Zebrafisch (Danio rerio), Ziege

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NHE7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-NHE7 Antikörper

Bindungsspezifität: N-Term

Sequenz: LGWGLRVAAA ASASSSGAAA EDSSAMEELA TEKEAEESHR QDSVSLLTFI

Homologie: Dog: 100%, Goat: 85%, Guinea Pig: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against SLC9A7. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human SLC9A7

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 725 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu NHE7

Target: NHE7 (SLC9A7) (Sodium Hydrogen Exchanger 7 (SLC9A7))

Andere Bezeichnung: SLC9A7

Hintergrund: Organelles of the secretory and endocytic pathways are distinguished by their luminal acidity, which is generated by the activity of an electrogenic vacuolar-type hydrogen ATPase. Progressive acidification of vesicles in the endocytic pathway is essential for the redistribution and degradation of internalized membrane proteins, such as ligand receptor complexes and fluid-phase solutes. It may play an important role in maintaining cation homeostasis and function of the trans-Golgi network.Organelles of the secretory and endocytic pathways are distinguished by their luminal acidity, which is generated by the activity of an electrogenic vacuolar-type hydrogen ATPase. Progressive acidification of vesicles in the endocytic pathway is essential for the redistribution and degradation of internalized membrane proteins, such as ligand receptor complexes and fluid-phase solutes. This gene is expressed predominantly in the trans-Golgi network, and mediates the influx of sodium or potassium in exchange for hydrogen. It may thus play an important role in maintaining cation homeostasis and function of the trans-Golgi network. This gene is part of a gene cluster on chromosome Xp11.23.Organelles of the secretory and endocytic pathways are distinguished by their luminal acidity, which is generated by the activity of an electrogenic vacuolar-type hydrogen ATPase. Progressive acidification of vesicles in the endocytic pathway is essential for the redistribution and degradation of internalized membrane proteins, such as ligand receptor complexes and fluid-phase solutes. This gene is expressed predominantly in the trans-Golgi network, and mediates the influx of sodium or potassium in exchange for hydrogen. It may thus play an important role in maintaining cation homeostasis and function of the trans-Golgi network. This gene is part of a gene cluster on chromosome Xp11.23.
Alias Symbols: NHE7, SLC9A6
Protein Interaction Partner: UBC, SCAMP5, SCAMP2, SCAMP1, SLC9A7,
Protein Size: 725

Molekulargewicht: 80 kDa

Gen-ID: 84679

NCBI Accession: NM_032591, NP_115980

UniProt: Q96T83