MTA2 Antikörper (C-Term)

Produktnummer ABIN2781484

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch MTA2 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Ziege, Meerschweinchen und Schwein und wurde in 1 Publikation erwähnt.

Kurzübersicht für MTA2 Antikörper (C-Term) (ABIN2781484)

Target: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Ziege, Meerschweinchen, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MTA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-MTA2 Antikörper

Bindungsspezifität: C-Term

Sequenz: ALTHLEMRRA ARRPNLPLKV KPTLIAVRPP VPLPAPSHPA STNEPIVLED

Homologie: Cow: 88%, Dog: 94%, Goat: 88%, Guinea Pig: 82%, Horse: 100%, Human: 100%, Mouse: 94%, Pig: 94%, Rabbit: 100%, Rat: 94%

Produktmerkmale: This is a rabbit polyclonal antibody against MTA2. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human MTA2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 327 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-MTA2 Antikörper (ABIN2781484)

Schiene-Fischer, Yu: "Receptor accessory folding helper enzymes: the functional role of peptidyl prolyl cis/trans isomerases." in: FEBS letters, Vol. 495, Issue 1-2, pp. 1-6, (2001) (PubMed).

Details zu MTA2

Target: MTA2 (Metastasis Associated 1 Family, Member 2 (MTA2))

Andere Bezeichnung: MTA2

Hintergrund: MTA2 modulates the enzymatic activity of the histone deacetylase core complex.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. This gene is found to be deleted in Williams syndrome.
Alias Symbols: DKFZp686F2281, MTA1L1, PID
Protein Interaction Partner: vpr, SUMO2, SUMO3, DNMT3B, DNMT1, NACC2, ZBTB16, UBC, RARA, ZBTB1, RNF2, GPHN, HNRNPR, TRIM28, PPP4R1, ROCK2, SPAG9, POLR2C, POLR2A, MAP4, RPP25, LSM8, GET4, LARP7, CD2AP, NR3C1, MTOR, EHBP1L1, RABEP2, BRCC3, SMEK1, ZGPAT, HDAC1, HDAC2, CSNK1E, MTA3, UBE3
Protein Size: 327

Molekulargewicht: 36 kDa

Gen-ID: 9219

NCBI Accession: NM_003602, NP_004730

UniProt: O94776

Pathways: Chromatin Binding